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51.
1. Alba, a white wing colour morph of butterflies of the genus Colias , makes fitness-related changes at several levels of phenotypic organization: physiology, development and behaviour. Two sympatric species of Colias are studied, which differ greatly in their frequency of alba vs its sister yellow/orange morph. How resource and time constraints on Colias interact with the morphs' different patterns of pupal resource allocation to alter the balance of the morphs' fitness components in the two species is discussed.
2. These species, C. alexandra and C. scudderi , differ in melanin-based solar energy absorption, in larval dietary richness and in local adult nectar resources. The two female morphs determine alternate thermal balance, internal resource allocation and behavioural effects in each species, thus changing the morphs' time budgets and fitness-component impacts between the species. In particular, female egg output differences between the morphs appears to reverse between species: alba fecundity is greater than yellow fecundity in C. scudderi , but alba is less than yellow in C. alexandra .
3. These differences are consistent with the large observed differences in alba frequency between the species. Some important questions about the selective regime maintaining a polymorphism here, rather than an alternation of monomorphisms, remain. 相似文献
2. These species, C. alexandra and C. scudderi , differ in melanin-based solar energy absorption, in larval dietary richness and in local adult nectar resources. The two female morphs determine alternate thermal balance, internal resource allocation and behavioural effects in each species, thus changing the morphs' time budgets and fitness-component impacts between the species. In particular, female egg output differences between the morphs appears to reverse between species: alba fecundity is greater than yellow fecundity in C. scudderi , but alba is less than yellow in C. alexandra .
3. These differences are consistent with the large observed differences in alba frequency between the species. Some important questions about the selective regime maintaining a polymorphism here, rather than an alternation of monomorphisms, remain. 相似文献
52.
MDR1 P-glycoprotein transports endogenous opioid peptides 总被引:3,自引:0,他引:3
MDR1 P-glycoprotein is generally regarded as an efflux pump for amphipathic toxic compounds. The question remains, however, whether certain endogenous compounds are also substrates for this transporter. Certain peptides have been shown to interact with MDR1 Pgp as well and we have therefore investigated whether endogenous bioactive peptides are substrates. We demonstrate here that the synthetic μ-opioid peptide DAMGO is a good substrate for MDR1 Pgp. In view of its low interaction with the membrane it is an attractive ligand for measurement of MDR1 Pgp-mediated transport activity in membrane vesicles. Various linear peptides with amidated C-termini were found to inhibit MDR1 Pgp-mediated DAMGO transport. This group includes endogenous opioid peptides such as adrenorphin and endomorphin 1 and 2, as well as the neurokinin, Substance P. The latter bioactive peptides have a relatively high affinity for the transporter. Transport of endomorphin 1 and 2 could be directly demonstrated by the uptake of the radiolabeled opioid peptides in membrane vesicles from MDR1-transfected cells with a Km of 15 and 12 μM, respectively. This opens the possibility that MDR1 Pgp is involved in the elimination and/or tissue distribution of these bioactive peptides. 相似文献
53.
Acid-promoted, selective production of 5-hydroxymethylfurfural (HMF) under high fructose concentration conditions was achieved in ionic liquids (ILs) at 80 °C. A HMF yield up to 97% was obtained in 8 min using 1-butyl-3-methylimidazolium chloride ([C4mim]Cl) catalyzed with 9 mol % hydrochloric acid. More significantly, an HMF yield of 51% was observed when fructose was loaded at a high concentration of 67 wt % in [C4mim]Cl. Water content below 15.4% in the system had little effect on HMF yield, whereas a higher water content was detrimental to both reaction rate and HMF yield. In situ NMR analysis suggested that the transformation of fructose to HMF was a highly selective reaction that proceeded through the cyclic fructofuranosyl intermediate pathway. This work increased our capacity to produce HMF, and should be valuable to facilitate cost-efficient conversion of biomass into biofuels and bio-based products. 相似文献
54.
Assessment of trap plants to regulate numbers of the European tarnished plant bug, Lygus rugulipennis, on late-season strawberries 总被引:1,自引:0,他引:1
Various species of plants in the family Asteraceae were shown to be hosts for the European tarnished plant bug Lygus rugulipennis and one, Matricaria recutita, was chosen as a potential trap plant for adults of this capsid species on their migration into fields of late-season strawberries from other host plants in July. There was a delay in the build-up of populations of nymphs of L. rugulipennis on strawberries surrounded by a barrier strip of M. recutita compared to those without a barrier, but overall there were no consistent reductions in populations of the pest. Numbers of L. rugulipennis on the trap plant were small until late August. In a similar experiment using an alternative trap plant, Medicago sativa, no significant reductions in the numbers of L. rugulipennis were found on strawberries with the trap barrier, despite large numbers of the pest insect being found on this trap plant.Although predatory arthropods such as spiders, Orius spp., and nabids, and hymenopterous parasitoids were found on the trap plants, there was no indication that they became more numerous on the strawberry plots inside these barriers than on those without surrounding trap plants. 相似文献
55.
Selection for phenotypic plasticity in Rana sylvatica tadpoles 总被引:1,自引:0,他引:1
Josh Van Buskirk Rick A. Relyea 《Biological journal of the Linnean Society. Linnean Society of London》1998,65(3):301-328
The hypothesis that phenotypic plasticity is an adaptation to environmental variation rests on the two assumptions that plasticity improves the performance of individuals that possess it, and that it evolved in response to selection imposed in heterogeneous environments. The first assumption has been upheld by studies showing the beneficial nature of plasticity. The second assumption is difficult to test since it requires knowing about selection acting in the past. However, it can be tested in its general form by asking whether natural selection currently acts to maintain phenotypic plasticity. We adopted this approach in a study of plastic morphological traits in larvae of the wood frog, Rana sybatica. First we reared tadpoles in artificial ponds for 18 days, in either the presence or absence of Anax dragonfly larvae (confined within cages to prevent them from killing the tadpoles). These conditioning treatments produced dramatic differences in size and shape: tadpoles from ponds with predators were smaller and had relatively short bodies and deep tail fins. We estimated selection by Anax on the two kinds of tadpoles by testing for non-random mortality in overnight predation trials. Dragonflies imposed strong selection by preferentially killing individuals with relatively shallow and short tail fins, and narrow tail muscles. The same traits that exhibited the strongest plasticity were under the strongest selection, except that tail muscle width exhibited no plasticity but experienced strong increasing selection. A laboratory competition experiment, testing for selection in the absence of predators, showed that tadpoles with deep tail fins grew relatively slowly. In the cattle tanks, where there were also no free predators, the predator-induced phenotype survived more poorly and developed slowly, but this cost was apparently not associated with particular morphological traits. These results indicate that selection is currently promoting morphological plasticity in R. sylvatica, and support the hypothesis that plasticity represents an adaptation to variable predator environments. 相似文献
56.
57.
Elliott Sober 《Biology & philosophy》1999,14(2):253-278
Modus Darwin is a principle of inference that licenses the conclusion that two species have a common ancestor, based on the observation that they are similar. The present paper investigates the principle's probabilistic foundations. 相似文献
58.
Dr. Christine Moseley 《Science activities》2013,50(3):26-29
In this activity, teachers in one state create and share an “exchange box” of environmental and cultural items with students of another state. The Environmental Exchange Box activity enables teachers to improve students' skills in scientific inquiry and develop attitudes and values conducive to science learning such as wonder, curiosity, and respect for different social perceptions. Teachers will be able to work beyond the limits of the classroom and introduce outside resources to help increase students' global awareness and promote respect for the culture and environment of diverse populations. Specifically, this activity can help teachers fulfill national Teaching Standards B, D, and E. 相似文献
59.
《Saudi Journal of Biological Sciences》2021,28(11):6289-6296
According Global Cancer Statistics 2020 GLOBOCAN estimates female breast cancer was found as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), and the fourth leading cause (6.9%) of cancer death among women worldwide. Identification of new diagnostic marker sharply characterize the tumor feature is intensive need. The present work was performed to investigate the involvement of the INF-γ + 874 T/A gene polymorphism in different breast cancer prognostic factors. Polymorphism detection analysis was performed on 163 subjects from breast cancer patients, 79 with inflamed cells of breast patients and 144 controls. The gene polymorphism was detected using the amplification refractory mutation system- polymerase chain reaction method (ARMS-PCR). The distribution of INF-γ T + 874A gene polymorphism shows strong significant association between INF-γ + 874 T/A genotypes TT in BC patients (ORTT: 6.41 [95% CI = 2.72–15.1] P < 0.0001) as well as strong significant association regarding T allele (ORT: 1.99 [95% CI = 1.43–2.76] P < 0.0001) when compared to the healthy control. In ICB group the strong association was noted with INF-γ + 874 T/A genotypes AT genotype (ORAT: 2.28 [95% CI = 1.22–4.29] P = 0.007). From the different histological BC hormonal markers the human epidermal growth factor receptor 2 (HER2) was showing significant association in INF-γ + 874 T/A genotypes TT (P = 0.03) and recessive model (TT versus AA + AT P = 0.03). Concerning different BC prognostic models, the poor prognostic one of luminal B, (ER+ve PR+ve Her2+ve) show significant association in the host INF-γ + 874 T/A genotype (TT, P = 0.03) and recessive model (TT versus AA + AT P = 0.02) when compared to the good prognostic hormonal status luminal A model, (ER+ve PR+ve Her2-ve). It seems that this is the first study that interested in correlate the INF-γ + 874 T/A gene polymorphisms in Egyptian BC patients. T allele, TT genotype and recessive model of the INF-γ + 874 T/A gene variants were documented as risk factors for BC pathogenesis. It may be used as practical biomarker to guide the BC carcinogenesis and risk process. 相似文献
60.
Zhihui Deng Jianxin Zhen Genelle F Harrison Guobin Zhang Rui Chen Ge Sun Qiong Yu Neda Nemat-Gorgani Lisbeth A Guethlein Liumei He Mingzhong Tang Xiaojiang Gao Siqi Cai William H Palmer Jonathan A Shortt Christopher R Gignoux Mary Carrington Hongyan Zou Peter Parham Wenxu Hong Paul J Norman 《Molecular biology and evolution》2021,38(6):2582
Human natural killer (NK) cells are essential for controlling infection, cancer, and fetal development. NK cell functions are modulated by interactions between polymorphic inhibitory killer cell immunoglobulin-like receptors (KIR) and polymorphic HLA-A, -B, and -C ligands expressed on tissue cells. All HLA-C alleles encode a KIR ligand and contribute to reproduction and immunity. In contrast, only some HLA-A and -B alleles encode KIR ligands and they focus on immunity. By high-resolution analysis of KIR and HLA-A, -B, and -C genes, we show that the Chinese Southern Han (CHS) are significantly enriched for interactions between inhibitory KIR and HLA-A and -B. This enrichment has had substantial input through population admixture with neighboring populations, who contributed HLA class I haplotypes expressing the KIR ligands B*46:01 and B*58:01, which subsequently rose to high frequency by natural selection. Consequently, over 80% of Southern Han HLA haplotypes encode more than one KIR ligand. Complementing the high number of KIR ligands, the CHS KIR locus combines a high frequency of genes expressing potent inhibitory KIR, with a low frequency of those expressing activating KIR. The Southern Han centromeric KIR region encodes strong, conserved, inhibitory HLA-C-specific receptors, and the telomeric region provides a high number and diversity of inhibitory HLA-A and -B-specific receptors. In all these characteristics, the CHS represent other East Asians, whose NK cell repertoires are thus enhanced in quantity, diversity, and effector strength, likely augmenting resistance to endemic viral infections. 相似文献